|
STRUCTURAL
BIOLOGY AND CHEMISTRY SYMPOSIUM
|
|
Friday 30th
October
|
09:00 - 09:30
|
Welcome
|
|
Chair Persons:
E. Eliopoulos - S.E. Zographos
|
|
09:30 - 10:00
|
Prof. K.R. Acharya:
Structural Molecular Biology Research at Bath – Contribution by Nikos Oikonomakos
through Athens - Bath link
|
|
10:00 - 10:30
|
Prof.
A. MacKerell: Optimizing ligand-protein
interactions via SILCS: Site Identification by
Ligand Competitive Saturation
|
|
10:30 - 11:00
|
Prof. D.I. Stuart:
The role of technologies in helping understand virus
structure and evolution
|
|
11:00 - 11:30
|
Prof. L. Somsák:
Approaching the nanomolar range with glucose
analogue inhibitors of glycogen phosphorylase: N-acyl-N’-β-D-glucopyranosyl
ureas and beyond
|
|
12:00 - 15:00
|
Lunch break and INSTRUCT meeting
|
|
Chair Persons:
I.M. Mavridis - A. Tsitsanou
|
|
15:00 - 15:30
|
Prof. A. Gimisis:
Exploring the Catalytic Site of Glycogen
Phosphorylase with β-D-Glucopyranosyl-Nucleoside
Inhibitors
|
|
15:30 - 16:00
|
Prof. L. Agius:
Physiological control of liver glycogen
phosphorylase by substrate and endocrine mechanisms:
the value of pharmacological tools
|
|
16:00 - 16:30
|
Prof. P. T.W .Cohen:
The phosphorylase α interaction with the hepatic
glycogen targeting subunit of protein phosphatase 1
as an anti-diabetic target
|
|
16:30 - 17:00
|
Prof. G. Fleet: Rare
and new monosaccharides: a bit of chemistry and a
lot of biotechnology
|
|
17:00 - 17:30
|
Coffee break
|
|
Chair Persons:
S. Hamodrakas
- V.
Skamnaki
|
|
17:30 - 18:00
|
Prof. L.N. Johnson:
The structural basis for control by phosphorylation
|
|
18:00 - 18:30
|
Prof. S.J. Tzartos:
Current knowledge on the structure of nicotinic
acetylcholine receptors and our own efforts
|
|
18:30 - 19:00
|
Dr. I.Μ. Mavridis:
High resolution structures of several 2[4Fe-4S]
ferredoxins explain the reduction potential of
[4Fe-4S] clusters
|
|
19:00 - 20:00
|
Dr. A.C. Papageorgiou:
Understanding proteins: A journey through structural
biology and chemistry
|
|
20:30 - 23:00
|
Dinner
|
|
|
|
Saturday 31st
October
|
Chair Persons:
A. Hountas- J.M. Hayes
|
|
10:00 - 10:30
|
Prof. A. Giannis: From
Homer to Hedgehog: Synthesis of Cyclopamine Using a
Biomimetic and Diastereoselective Approach
|
|
10:30 - 11:00
|
Prof. E. Eliopoulos:
Odorant Binding Proteins. The mosquito olfaction
target
|
|
11:00 - 11:30
|
Prof. M. Wilmanns:
Catalytic promiscuity in M. tuberculosis
|
|
11:30 - 12:00
|
Prof. J.P. Praly:
Glycochemistry, glycomimics, and amino acids in the
context of diabetes
|
|
12:00 - 12:30
|
Closing remarks
|